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Amber Heard emerged as a shit ass whore when she went poopies on Johnny Depp's bed.
A disparaging remark toward a woman that is much harsher than just "whore" (i.e., a shit ass whore is a prostitute who doesn't wipe her butt after defecating). Can be preceded by "fucking" for maximum effect.
Don't worry about her, man. She's a fucking shit ass whore. You can do much better.