A euphemism for "getting drunk". Used to describe the state at which someone starts to say whatever they are thinking, no matter how ridiculous it sounds.
Dave - "Has anyone ever wondered why the students at Glasgow and the students at Strathclyde cant just be friends? What is the point in this silly rivalry when we're all living in the same city?"
Dave's friend - "Somebody take the bottle off Dave, he's starting to get philosophical."