- Regarding female arousal; a person who causes sex drive and arousal to diminish in an instant.
- A boner killer for women.
"So I was totally about to hook up with Mike last night, until he took his pants off. Total twat flop."
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The lower-body equivalent to a nip slip - In other words, when accidental clothing movement causes a woman's genitalia to become at least partially visible.
After riding the waterslide, she was totally suffering from a twat flop.
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