unspool

To lose one's mind as a result of a major emotional shock, from the pilot episode of the television series Wonderfalls:

(Jaye discovers that her sister Sharon is a lesbian)

Jaye: Does Mom know?

Sharon: She would unspool!

Jaye: Can I tell her?

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unspooling

A word used by 4chan losers to describe someone they believe is "going crazy".

LOL I caught you online on the forums at 3 AM UR unspooling

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