"What does that have to do with the price of tea in China?" is an expression which denotes that what the other person just said is completely unrelated to the original topic.
Person A: President Bush is the best president EVER!
Person B: No, he's not! He's the worst president!
Person A: Why do you say that?
Person B: Umm, I just bought a guitar.
Person A: Well, what does that have to do with the price of tea in China?
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