Twisted or contorted out of normal shape or form. Usually used to refer to a style of antique ornamentation or the should-be carcasses of wriggling, horrid eels found laid abreast 'cross the coasts of innsmuth.
Person 1: I'm telling you dude, writhen tendrils are lashing at my door at night.
Person 2: You really should get off that benadryl bro.
Person 1: Yeah, I should.
THEM: Yeah, he should.