To let go of all restraints or inhibitions especially with respect to physical activities or sports.
If a fan sees that an athlete is holding back or could use some encouragement he might yell out: "Take the leash off Huey!"
My girlfriend is usually pretty restrained in bed, but not last night. She really took the leash off!
To poo and really relax afterwards
Hey Steve, I just went to take a load off and now I am hungry.
An excuse girlfriends use to ditch you and hook up with other guys
My girlfriend decided to “take the night off” with her ex boyfriend
Taking the virginity from young men
I was taking the hat off from a 19 year old last night
To throw up a little bit to make yourself feel better when you’ve been drinking.... prematurely to when one would “pull trig”
Oh boy that pregame hit different. I need to take the top off!
A girl grinding on a dude while holding her proverbial cowgirl hat in one hand
-so what did you and Daniel do last night?
-all we did was take the hat off
A threat aimed at someone who is touching you in an uncomfortable or aggravating way.
guy 1: Look, just cuz the hottest girl in school dumped you doesn't mean anything. *puts arm around guy 2*
pissed off guy 2: Take it off before I break it off.