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To masturbate
The act of masturbation
Guy 1: Did you see Stacey?
Guy 2: Yeah, total nipple slip! I'm totally going to knuckle up to that later
To prepare to kick another's ass, getting prepared to engage in fisticuffs
If you get up in my grille, you best knuckle up, motherfucker
a phrase uttered in encouragement meaning: "muster your courage, intestinal fortitude and love for the American-way in preparation for an upcoming (or admist a) challenge
of epic proportions!"
(uttered many times by one of the dudes in the movie "The Matrixs:Revolutions" during battle
against the electro-mechanical foe)
"Here they come boys ... Knuckle up!"
To Make Reddy, To Make Preparation, To Assemble, To Focus on the objective, To concentrate
Tomorrow's the big day people, there's no room for mistakes, so all of you better Knuckle-Up!
Guy 1 "i was at the bar chillin talkin to this girl after the band played, then this dude looked at me like he wanted a problem."
Guy 2 "what happened?"
Guy 1 "I had to knuckle up then his boy pulled him back."
major shrinkage of a man's penis to the size of a finger between two knuckles
Wow it's cold out, I can barely see my dick, it must be knuckling up.
I don't have a micropenis, it's just knuckling up!