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The act of uppercutting someone, while yelling shut the fuck up
person 1:haha i heard during school today, john gave donnie a shut the fuck uppercut
person 2: OW! that must have hurt...
a prolonged version of stfu, usually used to express further anger.
"oh my god! so i heard jenny talking about cindy saying she was going out with brad and sarah was cheating on him with ricky and-"
"SHUT THE FUCK UPPERCUT!"