take a load off

to sit down and/or relax

Come on in and take a load off.

take a load off

to rest by sitting down

"Do you mind if I take a load off? I have been walking forever.

take a load off

To calm down by means of masturbation and ejaculation in stressful situations.

Come on John, Calm yo' tits, go home and take a load off.

take a load off

To poo and really relax afterwards

Hey Steve, I just went to take a load off and now I am hungry.