Put your dick, fingers, leg, a bottle or whatever you want in somebody's ass.
Mike: Hey asshole (showing a finger)
Bob: Hey, this up in your ass
An apology for clingy or needy behavior such as blowing up someone's phone, or knowingly pestering someone for their attention.
Me: sorry I've been up your ass today.
Friend: thanks, but you need to not text me so much.
When a group of people are talking shit about you.
CAL:"I got it now 'you're a virgin"
ANDY:"YOU GUYS ARE SO UP YOUR ASSES"
An insult that is used to show disinterest, or frustration. To dismiss a wrongful statement or action.
Bill Gates: I have so much more money than you!
Random person: Go shove it up your ass!