A negative adjective to describe someone or something with one or more of these traits: slim, tall, irrational, difficult, problematic, naive, overall shitty.
"Don't be such a twimbly bitch!"
"I'm having a pretty twimbly day."
"This is such a twimbly fucking test."
When you put toothpaste on your partner's asshole and eat them out.
Girl: Oh my god! Last night my boyfriend gave me a wet brush! I can still feel the toothpaste!