A multiuse, versatile word just like "fuck". Its meaning is contextual and also up to interpretation. Some claim that it represents the main character in the game by 3D realms, Duke Nukem. Basically just do anything like Duke Nukem would.
1. Just Duke It!
2. I duked that guy right in the face.
3. Duke it out.
4. I'd duke her.
5. I pulled a duke in there.
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