Maus

Real Meaning:
German super heavy tank of WW2 aka Panzer VIII with a 12.8 Pak 44 Cannon with the tank weighing around 188 tones

Meme/Gaming Meaning:
A freaking heavy tank made out of pure German steel and tracks made out of Mice that can crush a modern M1A2 Abrams. Stay away from it or get panckaked!

Hitler: Einen neuen Panzer bauen (make a new tank!)
Engineer: Tiger II?
Hitler: Nein
Engineer: Capture KV-2s
Hitler: Nein
Engineer: A tank made out Cheese and let mice eat it and call it MAUS
Hitler: Jawohl!