Whenever something really turn you on, hooks you, intrigues or interests you, that thing "fucks your shit up." Only use for major things, not minor things; i.e., you wouldn't say "Cheetos fuck my shit up" unless they literally feel orgasmic in your mouth. And, yes, this idiom allows sarcasm. *Can be referred to as an acronym, FMSU.
Angelina Jolie fucks my shit up."/"Man, whenever I see a girl in a corset...whew! Fucks my shit up."/"Camaros fuck my shit up. They're so gnarly."/"Deftones. FMSU.
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