A cocktail made by combining Whiskey and Yoo-hoo chocolate beverage.
Jean: "Would you care for a Scotch, my friend?"
Gene: "No thanks, good fellow! I think I'll have another Whoo-hoo."
A cocktail made from Jameson and Yoohoo.
Friend: Is there banana flavoring in this J-hoo?
Bad Friend: Nope. Just Jameson and Yoohoo!
Giving someone a substance (especially psychedelics, like acid) without their knowledge nor consent.
"Chad is so square, he really needs to have his mind opened. Let's add some acid to his beer, and give him a ghost dose!"