Similar to getting 'vexed' or angry/frustrated. Its an old(ish) word, and is generally used in a way of expressing your angriness at anything and everything.
Johnny: For fucks sake I'm so irate!
Jimbo: Why dude?
Johnny: Just found out I'm adopted
Max: Give me my hat back before I throw my bellend in your eyes, you don't want to see me irate!
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