Your mom is a slang term for a prostitute or slut. This insult is only used by retards who think they are the king of comedy. But they are only the king of not getting laid
Your Nan is a comeback which is not just worse than your mom but more annoying. It is only used by people who were dropped when they were babies as a cheep comeback because they are more brain dead than a hedgehog on a motorway full of fast moving lorries.