Pick up that dollar, sometimes followed by bitch or hoe.. can refer to a person, a situation, a comment or reply to a conversation when you don't think much of them or what is being said. It can mean an event, person, thing or situation not worthy of your time. It is can be a condescending remark comparing the person, situation or event to a stripper , whore picking up money off the floor.
In response to the stripper who said "you ladies are stupid for sponsoring a lap dance for your guys"..the ladies replied, "hoe, pick up that dollar "