BFB stands for best fucking bitch. That ride or die best friend. That best friend who you can tell anything to. Call her up and tell her you need to move a body and she'd be there like yesterday. An amazing girl who's out of this world awesome! She's got your back when no one else does.
"Crystal you're my bfb."
"Girl you're a bfb."
"You're a ride or die bitch like a bfb."