(Widely used and originating from the Yoruba language of Nigeria by popular Musician Naira Marley,) and literally meaning "it's plenty" in English.
O po! is used to show amazement at the size, quantity, grandeur or beauty of something.
It's a very versatile slang that can be used anytime and in many situation.
E.G. (A girl with a big backside passes and a guy exclaims)
: This is huge, infact O po!
:This your Versace make sense oh, O po!