To be broken up with by one's spouse or significant other. The phrase is based on the very common phenomena where a wife will leave her husband if he eats too many calzones
"Have you heard about Dave? He's been sad and lonely ever since he ate too many calzones."
When youâre stalking someoneâs pictures on social media and accidentally go back to when he/she was underage.
Friend 1: Man, she looks a little weird in this picture...
Friend 2: Dude, that picâs from 5 years ago! Youâre in the danger zone!
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