A poorly executed handshake, in which one or both of the hands involved are limp while shaking. Apparently it makes the sound ay-sop when they meet. It originates in Southern Wales, it is also said in places where Welsh would migrate. However it is a very rare saying nowadays. So expect weird looks if you make use of the phrase.
"Well doctor we really blundered that handshake. Twas a real aesop."
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