Same meaning as wordmashedword, as in some one who is completely intoxicated.....usually on drugs of any kind beside alcohol.
Don't give him any more, he's mash up!
The after effects of a night out with no sleep/too much drink/too many drugs etc.
He went raving last night, he came into work this morning looking messy.
Someone who tends to fight a lot and fight well is sometimes known as being grimy.
Yeah, Jason is grimy, I had to hold him back a few times out there!
Shit, Andy just went grimy on that kid!