Alphabet Soup

A concoction of multiple and many drugs that usually result in deadly overdoses that often take ones life.
Ex: "Mr. Heath Ledger died as the result of acute intoxication by the combined effects of oxycodone, hydrocodone, diazepam, temazepam, alprazolam, and doxylamine," the office said in a short statement.
- CNN

“He died after a night of alphabet soup. They found Meth, Fentanyl, Cocaine, Alcohol, and Xanax in his system”