When someone gets so drunk that when they cannot stop laughing it sounds like they are a asthmatic hyperventilating. Alphabetisism most frequently occurs from drinking too much Sicilian white wine!
It can also be more simply used to described getting really drunk.
Georgy: *Is laughing but taking continuous short shallow breaths, sounds like she is struggling to breath*
Stephen: Georgy are you alphabetic?
Or
Stephen: I want to get totally Alphabetic tonight!!!!
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