In general, a term referring to a metropolitan area of any relatively major size; usu. a metropolitan area significant for being the major city in one's state or region OR for being the city in which one resides or spends the most time.
In South Carolina, "the Metro" refers to Columbia, as it is the largest city in the state and is a popular destination for shopping, entertainment, nightlife, etc. for people all throughout the state.
Dominique: Where you at, son?
Dwayne: I've been down at the Beach, but now I'm headed back to the Metro.
Dominique: Word. You wanna hit up the spot tonight?
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