1. A situation or event that can be generally predicted as doomed to fail or to go horribly wrong.
2. A statement or other action by someone that is completely retarded or offensive to others.
1.
"We should try and jump off the roof into the pool."
"We aren't even drunk yet, this whole idea is no-kosher."
2.
"I can't believe that lard ass is taking so long to walk to her car."
"Dude it's no-kosher to talk about people like that."