An indication of disgust toward, or warning against hooking up with a particularly disgusting slut. She is so gross that upon seeing her and/or learning about her numerous sexual partners, you feel it's only safe to strap up with at least sixteen rubbers and stay a mile away from her pussy or more at all times to avoid getting a severe case of VD.
Tom: Dude! I think I'm gonna score with Kendra at Mike's party tonight, can't wait to hit that shit raw!
Jerry: You gotta be fuckin' kidding me. Oh well, have fun getting sloppy thirds 20 minutes after the party starts. I'd strap on 16 a mile away.
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