(1)To be crossed up is to be falling for a member of the opposite sex without being able to stop it. Compare to being "twisted up in the game," and whipped. You are crossed up if you keep thinkin about that special someone and you can't get them out of your head.
(2) To get juked in basketball, or consummately wrongfooted so that you look stupid.
(1) "dude I've been hangin out with Lindsay so much recently. I'm fairly crossed up..."
"You cant get crossed up too easily man, these girls will play you without thinkin twice.
(2) "Get crossed up, stay crossed up fool"
"Iverson just crossed that guy up like nobody's business"
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