A term used by a woman meaning which can have different meanings like "oh my gawd! I can't believe someone could be so stupid!", "how could somebody be so oblivious?! Pay attention! " or "how could somebody be such a careless ass hole."
1. Friend 1: "That chick has slept with 20 different people this week and asked how she got an STD!"
Friend 2: "WOW!"
2. Girl: "Seriously? She has liked you for over a year and you're just now figuring it out?! Not only have people been talking about forever she's can't keep from acting like a spaz when you are around!"
Guy: "No I didn't know"
Girl: "WOW!"
3: Friend 1: "He cheated on me three times and when I found out said I was the most useless thing on earth and then left"
Friend 2: "WOW! "