someone who has taken a lot of pill-form drugs. pilled up refers to the way the person looks after taking drugs. similar to the expression drugged up, but is used to describe a higher drug class, i.e. ecstasy is a class A drug and is a pill. can also be used to describe a general drug high. common expression used at raves and in clubs.
He was so pilled up last night
That is one pilled up chav
you look pilled up
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