dead to rights

When Brad's got you really good, and there's no longer a way out of a situation. You're in his crosshairs.

Me: "Mom and I went for ice cream last night, and it was delicious, however when I got home I spilled some on my rug"
Brad: "I was with your Mom last night, so we know that wasn't ice cream on the rug."
Me: "Shit. Brad's got me dead to rights."