The psychological disorder of being unable to remove one's head from one's ass (i.e. cannot see what is right in front of their face).
"Wow, if that person with Cranial Rectal Inversion farts, they're going to completely asphyxiate themselves!"
"Don't eat beans if you've got CRI."
"You'll need some Preparation-H to help get your head out of your ass."
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