To render your computer useless, as useless as a brick.
Usually the result of tampering with the insides and doing irreversible damage. Bricking your hardware leaves you with a new paperweight. Can be the end effect of a faulty flash or firmware update, a modification (mod) gone bad or being struck by lighting, to name a few.
He managed to get his new iMac bricked while trying to boot WinXP on it.
I tried to change graphics cards while my computer was running but I only managed to get my machine bricked.
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