Term used in reference towards a chick that has been more than likely around the world and back in the slut/skank/whore department...which has taken a total on her physical condition either down or upstairs but usually both.
Jack: Yo man check out that blonde hotty gettin all crazy over there, you think i could get that?
Blake: Dude wtf is wrong with you man?! Look at all that caked up makeup...don't be fooled by that worn out trash, she's gotta be a total "High Mileage Ho."
Jack: Good call man, she does seem a little worn around the edges, keep my drunk ass away from that tonight.
Blake: Likewise.
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