A sizeable volume of drugs (particularly marijuana) that someone is is in possession of.
Hit up my dawg Manny. He's got loud.
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One who spreads misery and maleficence. An unchivalrous, debased person with no sense of dignity or honor.
Knight 1: "Watch out for that neer-do-well. He has tried to lie to and to cheat us before."
Knight 2:"Is there no rest for a crestfallen malefactor?"