upsettion

(pronounced upset-shun, sounds like obsession)

This word is used when you have many things upsetting you, and the main thing would be your upsettion and you are obsessingly upset by your upsettion.

There is so many bugs I dislike, but spiders are my upsettion.

I disliked her points she made on her presentation, but her misspellings were my main upsettion.