AFS

Alpha Female Syndrome; Being in a situation when you're hitting on a girl but her friend is an alpha female, thusly cockblocking you and stifling any chance you had of getting laid.

ex 1:
Guy 1: I was talking to Sara and it was going great, but Betty came along interrogated me, then made Sara and the rest of the girls at the party leave.

Guy 2: Dude, that's a shitty case of AFS

ex 2:
Guy: So hey, do you want to head back to my place?

Girl 1: Sure, sounds good

Girl 2: Hey guys, I think I remember you, do you remember my name?

Guy; Umm, I don't think we met but..

Girl 2; No? Hey Jenna, let's go home. we're leaving. now.

Guy: That bitch gave me a one-way ticket to blue balls. Fuckin' AFS

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