When you're so smart your brain is disfunctional.
Wow that guy has severe up syndrome!
'Doing up' means to to something to its full extent. Normally something one wouldn't regularly do.
Example being, a person is baby-sitting their niece/ nephew and but is asked to come out with friends:
Person 1: Yooo come through this party tonight man'
Person 2: Ahh I can't man, I'm doing up uncle duties and shitt
Opposite of being dick down, similar to fucked up but only this relates to sex.
To be such a turn-off or fucking up so badly you couldn’t get laid
Basically screwing up so badly you couldn’t screw them.
Person A: dude I couldnt get her wet last night so she left early
Person B: man...you dicked up
Repressed or inhibited.
Due to his sheltered life under his parents' protection, he was very pent-up in the way of romance.
to have a good time; party
"Let's all go over to Jake's house party and bust it up with the honeys there!"