A meme card is based on a card game called uno, Under the official Uno rules, when an Uno reverse card is played, the direction of play is reversed. If the play was going clockwise, it now goes counter-clockwise and vice versa and so it become meme which called "resist" or "no u"
Person 1: bro have you seen Joe?
Person 2: what's Joe? <--using Uno Reverse Card
Person 1: who's Joe* <still didn't realize he has made a giant no u mistake
Person 2: JOE MAMA (cannot resist by saying who Joe mama anymore)
Person 1:*think again of what he did in his life*
A very strong weapon no one can avoid.
Bully: Yo mom so stupid she took a spoon to the super bowl!!!
Me: *uno reverse card*
Bully: IU IUD O HIUOX o OUIG Tyi oce iuG guyi!!!!!!!
The ultimate comeback no one can reverse
Guy 1: Ur mommy in ma bed yo
Guy 2: No u
Guy 1: UNO REVERSE CARD
Me: Hey, look there's a zombie behind you!
Some random dude that's a complete bitch: No U
Me: Uno Reverse Card
Some random dude that's a complete bitch: Gets turned into a zombie then I kill him and the other zombie.
The Reverse card is a special card in the game of Uno that can change the direction of play. When played, it reverses the order of play, so that players must now play cards in the opposite direction than they were previously playing. For example, if players were playing clockwise before, they will now play counterclockwise, and vice versa.
Me:*harrasing my friend and saying no u*
My friend:*pulls out the uno reverse card*