A rude way to tell someone go away or leave them alone used especially in Australia.
Jimmy: Hello Logan ! I'm calling you with Graffiti Removal just wondering ,if you would consider getting rid off fuck symbol on the wall of your home made by my son the other day?
Logan:Piss off, mate .
Piss off is a two word idiom, usually utilized when an unsuspecting person finally realizes that they have had a gut full of another and their 'state' has passed the point of just being 'pissed off' at them. arriving instead at the point of no return, do not bother passing go because there will in no way shape or form be 200 dollars or 200,000 dollars waiting for one of THE most miserable performances of a lifetime performed by THE single, stupidest person. No hyphen necessary. Can be applied to more than one person at a time.
Also see: "Eat shit and die". A similar intention and application with a little more direction and guidance for the socially challenged and terminally confused.
Singular: Here's an idea, jackass...why don't you piss off.
Multiples or more than one: It might be a good idea for y'all to piss off.