1) When someone gets excited playing a card game (ie Monopoly Deal) and spills food on themselves.
Dammit, you spilled food again! What a Derp Mah
that one motherfucker who makes music
Person 1: Yo did you see the new polar derp album?
Person 2: it's trash as fuck
A gay dude
Aka Peder which means Gay in Serbian
AHAHAHAH he's derpe
Grizzly Autistic Joe - derp. The derp is just a phrase with no meaning besides derp and hitting ur hand against your chest in a stupid fashion.
GAJ-derp casts confuse ray! But enemy casts WOW back! It's super effective!
The act whereby one tries to do something, but will fail without a doubt.
Daniel: Watch me get this clutch on CS:GO!
*Get's AWP'ed*
Jason: I knew you'd pull a derp.
When you take a shit and the outcome looks like Eli Manning.
Dan ate a bunch of Indian food and had a record setting Derp Drop. It was a spitting image of Eli Manning.