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A disorder in which a person has a face that makes you think he/she is a bitch. Said person might not actually be a bitch, but they look like one. BFS can be used for short.
Chris: Wow, that girl has a severe case of Bitch Face Syndrome.
Mandy: Yeah, she looked pissed off for no reason.
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A common condition where pulling a straight face makes you look like a serial killer.
Why do I look like I have bitch face syndrome? Uh oh! Looks like I'm gonna be a serial killer!
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Where a teenage daughter is spoilt by her mother resulting in her becoming a snob and in the process becoming a bitch towards her mother.
Dude: "Did you see what she said to her mother?"
Dude2: "Yeh! She must have a case of princess bitch-faced syndrome!"
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Where there’s nothing wrong with you but everybody thinks there is because you have a bitch face
Omg that girl is always looking at me wrong . I think she has chronic bitch face syndrome