The antonym of bless up, indicating a feeling of disappointment and/or hopelessness.
Karina: "I haven't pooped in four days."
Abbie: "Bless down."
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When you're doing missionary position with a girl but you have bad aim and accidentally slip it into her asshole.
Me and my girl were doing missionary but she was extra lubed up and I slipped and ended up Blessing the Rains Down in Africa