Exclamation that describes displeasure on the part of the speaker due to something being distasteful or otherwise sickening or displeasurable. From valspeak, so somewhat archaic. Usage these days is considered silly.
Oh, gag me with a spoon! Look at the zits all over that nerd's face!
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something you would like to do if something is grossing you out severly
"I hate watching dating reality shows---gag me with a spoon!"
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a phrase used to describe how unpleasant a situation may be
Hey jess, remember when you dated Evans?
Yeah, gag me with a spoon.
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An expression you say when you're in disbelief
Person 1: Did you know that dogs can't look up?
Person 2: Well gag me with a spoon and call me Criss Angel! I didn't know that!
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