The worst kind of sexually-transmitted disease you can possibly get.
It's a mixture of Gonorrhea, Syphilis, Herpes, and the Clap.
Pronounced: Gone-a-sif-a-herp-a-clap
It is also customary to clap once when somebody says this
Man 1: Dude, that girl is a total slut...she freaking gave me Gonnosyphiherpeclap.
Man 2: *Claps hands once*
Man 1: What the fuck was that for?
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