acronym for 'Hit it and Quit it' usually in reference to one night stands during sex. Having sex with a person then having no other relationship.
Mike: Yo man I H&Q Britney last night!
Tom: haha, that bitch is such a whore.
Mike: She liked it though. OH SHIT SHE'S CALLING ME.
Tom: Don't answer it.
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hit and quit. to have sex with a female/male and stop talking or interacting with him/her
i H&Q that bitch!