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When you eat spoiled and/or rotten food at McDonalds and later get diarrhea
Crap, now I have McDiarrhea from eating that Big Mac.
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When you get bad diarrhea after having a McDonald's burger.
"Oh fuck me man, I just shat my insides out cause of that damn big mac."
"Sounds like a case of McDiarrhea."
The diarrhea that creeps up on you suddenly, yet violently, following the consumption of McDonald's.
I ate a Big Mac for supper and woke up to the cold sweats and a massive case of McDiarrhea.
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