1. Anything negative involving current female WWE superstar Rhea Ripley. The O.C. (AJ Styles, Luke Gallows, and Karl Anderson) have used this phrase on Raw several times as part of their rivalry with The Judgment Day (Finn Bálor, Damian Priest, Dominik Mysterio, and, of course, Rhea Ripley).
2. When your ass is about to burst and you cannot piss first.
1.
AJ Styles (to Gallows and Anderson): Guys, I think we got a Rhea problem on our hands.
Karl Anderson: Wait, what? Are you saying you got the tummy bug?
AJ Styles: I was talking about Rhea Ripley, dumbass.